Right Turn: Time to stop the bleeding

Author: Roshan Yoganathan, 04/17/14

Recently Revmedx, a pioneer in the biomaterial wound dressing field, made some waves with the commercialization of its product XStatTM . XStatTM received a lot of press because of its FDA approval for use against gunshot wounds and shrapnel-related injuries in the battlefield. It is used to help stop the bleeding and help sustain the…Read more

Testing stem cells in the clinic – a role for publicly funded trials?

Author: David Kent, 04/15/14

> In February this year, the biggest stem cell trial for heart attack patients was begun and will involve over 3000 patients from 11 different countries in Europe. The BAMI trial (the effect of intracoronary reinfusion of Bone marrow-derived mononuclear cells on all course mortality in Acute Myocardial Infarction) aims to demonstrate whether or not…Read more

Right Turn: Bringing stem cells to (fictional) life

Author: Lisa Willemse, 04/11/14

> I’ve been thinking a fair bit about the “personalities” of stem cells in recent weeks — specifically, the characteristics of stem cells that might translate into a persona or a fictional character of some sort. It’s with good reason, of course: The Stem Cell Network is in the process of creating a traveling science…Read more

Cell lines, patient samples, and cultures – oh my!

Author: Sara M. Nolte, 04/08/14

> The thing that is so intriguing about cancer stem cells (CSCs), from a cancer researcher’s perspective, is their powerful potential as therapeutic targets. While CSCs can create or regenerate tumours (causing relapse in some patients despite our best efforts to prevent it – more on this in my previous post on CSCs), they also…Read more

Right Turn: Autism, Stem Cells and the Tooth Fairy

Author: Stacey Johnson, 04/04/14

. This intriguing title is not completely my own. It is a shorter version of Alysson Muotri’s  (UCSD) title from a presentation he gave to the governing Board of the California Institute of Regenerative Medicine on March 13, 2014: “Reversing Autism in the Lab with Help from Stem Cells and the Tooth Fairy.” Dr. Muotri…Read more

The Hunter and the Bear: Italy’s Stamina and Vannoni, as Aesop would have told it

Author: Alessandra Pasut, 04/02/14

Editor’s note: Some of the links included are Italian language sources The case involving Stamina Foundation and the legitimacy of its stem cell treatments has been one of the most discussed and controversial issues in the international stem cell policy scene. Tomorrow, April 3, Davide Vannoni, Stamina’s founder, will be expected at a court trial…Read more

Right Turn: Stripping down to the muscle

Author: Lisa Willemse, 03/28/14

> Michael Rudnicki has been studying muscle biology for a long time… all the way back to his days as a graduate student. In this time, he’s contributed greatly to our understanding about muscle formation and the molecular “switches” that guide a stem cell’s decision to develop down the pathway towards muscle or brown fat….Read more

Right Turn: Lab parodies to cell-ebrate spring

Author: Stacey Johnson, 03/21/14

. Hopefully this is a happy Friday for you and Mother Nature has sent you a healthy dose of spring to acknowledge the date on the calendar. Regardless, whether you are rejoicing in warmer temperatures and reveling in bird song or cursing vile weather as you layer appropriately, Right Turn is feeling optimistic and has…Read more

Immunology and insider dealing: How macrophages trick your body into accepting biomaterials

Author: Holly Wobma, 03/18/14

> I’d like to make an unusual proposition. It’s occurred to me that our bodies are kind of snobs. Personality aside, our bodies are extremely particular. They reject tons of bacteria and viruses, while accepting others. They reject foreign tissues but can sometimes be coaxed into accepting them when bribed with medications. I suppose you…Read more

Right Turn: Eye candy, a.k.a. retinal stem cells

Author: Lisa Willemse, 03/14/14

> The eye is a complicated, fascinating  and important organ. Historical records indicate that the Hindus of ancient India began performing cataract surgeries as early as the fifth century BC and that both the Egyptian and Greek civilizations had developed procedures for treating various forms of blindness. Two thousand years later, we continue to look…Read more