Right Turn: End of an era, almost

Author: Lisa Willemse, 03/27/15

> This is my final post as co-editor of Signals, and in sitting down to draft it, I found myself struggling to find words. How do you sum up six years of blogging? Quite simply, you don’t. However, as this also marks the end of the Stem Cell Network’s involvement with Signals, it was suggested…Read more

Update from the Clinic: February

Author: Mark Curtis, 03/25/15

. Welcome to your Update from the Clinic for the month of February. Northwest Biotherapeutics received approval from Health Canada to proceed with its ongoing Phase 3 clinical study in Glioblastoma multiforme at clinical sites in Quebec. Sangamo and bluebird bio both had news on the regulatory progress of their respective beta-thalassemia programs. Kite Pharma…Read more

Such a long journey – Europe approves retinal cell therapy based on decades of good science

Author: David Kent, 03/24/15

> At one of my very first Canadian Stem Cell Network Annual General Meetings, when I was just a couple of years into my stem cell biology training, I remember sitting down just after lunch when a jovial Italian man sauntered up to the stage and apologized to the audience for the timing of his…Read more

What’s in a name? A cancer stem cell by any other name is still a stem cell – or is it?

Author: Sara M. Nolte, 03/23/15

> I have previously written about the phrase “cancer stem cell,” and how it can be misleading for researchers and the public alike. As scientists, we go through great pains to be specific in our use of ‘cancer stem cell’ (CSC), referring to a cell that possesses the stem cell abilities of self-renewal and multi-lineage…Read more

Right Turn: No horsing around with this grand gesture

Author: Stacey Johnson, 03/20/15

. American media and telecom billionaire John Malone, along with his horse-breeding wife Leslie, have generously donated U.S. $42.5 million to Colorado State University to launch the CSU Institute for Biologic Translational Therapies to develop regenerative medicine treatments to benefit animals and people. The university says the new institute “will be unique in its focus…Read more

No more monkeying around – promising results using stem cells to treat Parkinson’s disease

Author: David Kent, 03/18/15

Earlier this month, Harvard Medical School researchers published a brief report in Cell Stem Cell, which showed in non-human primates – in this case monkeys – that Parkinson’s disease symptoms could be alleviated using stem cell therapy. Using induced pluripotent stem (iPS) cells made from monkeys, they were able to make neurons outside the body…Read more

Grow your brains: Neural stem cells in 1 minute.

Author: Lisa Willemse, 03/17/15

> Many of us only become acutely aware of our brain when it’s not working quite right. Like, say, if we have a migraine, or are diagnosed with a mental illness. Or we fall on the ice and give ourself a concussion that affects our vision, motor skills and other cognitive functions (as was my experience…Read more

Cell Therapy 2.0 – warts and all

Author: David Kent, 03/16/15

> The last 15 years of stem cell research have been full of hope and promises – some of it delivered upon, most of it not quite there yet, and some of it miserably failed. I guess that is to be expected in a highly experimental area of medicine, but one of the most striking…Read more

Right Turn: Super Cells in Newcastle

Author: Lisa Willemse, 03/13/15

> Super Cells has grown wings and flown over to Newcastle. Yes, I know, you’re struck dumb at the improbability of this terrible metaphor, but far less than I am: having reviewed every word, every animation, every image, every concept of this exhibit, I’m completely baffled at how the feather follicle stem cells snuck in there…Read more

Hot off the press: DNA-based bioprinting of tissues

Author: Guest, 03/11/15

. By S. Amanda Ali, PhD What do biomaterials mean to you? For this orthopaedic scientist, the first thing that comes to mind is the total joint replacement: artificial knees, hips and shoulders made from a variety of materials to reproduce joint function and suit each patient. Introduced in the 1960s to the field of…Read more