Stem cells as the road to repairing Multiple Sclerosis

Author: Lisa Willemse, 06/02/15

. A clinical trial set to begin this month in Ottawa will test the safety and efficacy of mesenchymal stem cells to stimulate repair of damaged nerves in MS patients. This article was published simultaneously on the Ontario Institute for Regenerative Medicine website. On any given day at the general campus of The Ottawa Hospital,…Read more

Right Turn: Crowdsourcing science – the power of many

Author: Guest, 05/29/15

. Camila Londono is currently an intern at CCRM, taking a break from working on her PhD at the Institute of Biomaterials and Biomedical Engineering at the University of Toronto under the supervision of Dr. Alison McGuigan. Her research focuses on understanding what governs the coordination of motion in groups of cells. She holds a…Read more

Regenerative Medicine Deal Review: April

Author: Mark Curtis, 05/27/15

. Welcome to your deal review for the month of April. There is no update yet on the fate of the Cellular Dynamics International/Fujifilm deal, but it appears that CDI made some effort to solicit offers from alternative bidders. Aduro made headlines, though, closing a *$136 million initial public offering (IPO) and opening on its…Read more

Update from the Clinic: April

Author: Mark Curtis, 05/25/15

. Welcome to your Update from the Clinic for the month of April. Mesenchymal stem cells took a hit as Athersys’ MultiStem came up short, missing its primary endpoint in a Phase 2 study investigating the cells for ischemic stroke. Juno Therapeutics continues to turn heads with its Phase 1/2 data in blood cancers. NeoStem,…Read more

Right Turn: Science is awesome

Author: Stacey Johnson, 05/22/15

. “Science is often flawed” is the first half of the title of an article by Julia Belluz and Steven Hoffman of Vox.com. Lately, it feels like there are lots of articles pointing out that science is flawed and scientists are too. The stem cell and regenerative medicine world is certainly not immune to this…Read more

Cellular Dynamics takes Fujifilm from cameras to combination products

Author: Paul Krzyzanowski, 05/21/15

. By now, many of you will have heard of Fujifilm’s USD$307 million purchase of Cellullar Dynamics International (CDI). This may seem like a major entry into the regenerative medicine (RM) space for a company that’s better known for its imaging technologies than something as complex as the cell therapy space. However, the move seems to…Read more

By all means, target the CSCs – but leave the normal stem cells out of it!

Author: Sara M. Nolte, 05/19/15

. I’ve spent a number of posts going on and on about how targeting cancer stem cells (CSCs) is the next big thing for cancer therapies, and how important it is that we study and learn all we can about them (know your enemy, right?). All of this has probably left you with at least…Read more

Right Turn: Research2Reality

Author: Stacey Johnson, 05/15/15

. It was big science news in Canada this week when Professor Molly Shoichet, the University of Toronto’s senior advisor on science and engineering engagement, launched a $400,000 social media campaign to highlight the work of Canadian scientists in various disciplines. Research2Reality is a public outreach effort that currently features basic research from six Canadian…Read more

What drives research in the field of biomaterials? Second in series

Author: Guest, 05/11/15

. An interview with Professor John E. Davies, University of Toronto. By Hamideh Emrani The second post, in my interview series with biomaterials experts, is with my Master’s supervisor, Professor John (JED) Davies. He is an internationally recognized leader in bone biomaterials, a serial entrepreneur, and a Professor at the University of Toronto’s Institute of…Read more

Right Turn: Don’t go breaking my heart (epigenetics could if it tried)

Author: Guest, 05/08/15

. By Camila Londono Camila Londono is currently an intern at CCRM, taking a break from working on her PhD at the Institute of Biomaterials and Biomedical Engineering at the University of Toronto under the supervision of Dr. Alison McGuigan. Her research focuses on understanding what governs the coordination of motion in groups of cells….Read more