Archive for October, 2010

Questions raised about XCell Center

Author: Stem Cell Network, 10/22/10

In recent years the Stem Cell Network has worked closely with its international colleagues to shed light on clinics offering “stem cell” therapies for which there is scant scientific evidence. One such initiative is A Closer Look at Stem Cell Treatments, a web resource created by the International Society for Stem Cell Research, and a…Read more

Till and McCulloch inducted into Science and Engineering Hall of Fame

Author: Stem Cell Network, 10/21/10

For those who follow this blog, you will no doubt know that we are great supporters of the work of Drs. Jim Till and Ernest McCulloch. So, we were thrilled to learn earlier this month that the “fathers of stem cell science” will be honoured today with an induction into the Canadian Science and Engineering…Read more

The tell-tale heart: Firefly genes for stem cell tracking

Author: Chris Kamel, 10/19/10

As mentioned in a previous post, in order to fully understand what’s happening when stem cells are used for in clinical or in vivo research, we need some way to track them, preferably in a non-invasive manner. This can be done with either reporter genes or some sort of traceable label, and would allow researchers…Read more

RNA-induction: A new method for iPS cell production

Author: Chris Kamel, 10/14/10

The reprogramming of differentiated adult cells into induced pluripotent stem (iPS) cells is accomplished by the expression of a small number of key genes. This is typically done by introducing DNA either by transfection or with viral vectors. Current methods, unfortunately, are not very efficient and run the risk of mutagenesis as a result of…Read more

Stem cells and high throughput screening

Author: Allison Van Winkle, 10/08/10

High-throughput screening, in which many cell culture conditions can be tested using a combination of robotics, control software, and/or highly sensitive detection, allows researchers to explore new ideas quickly; thousands of combinations can be efficiently tested for toxicity, cell viability, proliferation or differentiation. Recently, high throughput screening was used to search a library of over…Read more

Special delivery: Getting stem cells into the spinal cord

Author: Katie Moisse, 10/06/10

Day two of the World Stem Cell Summit featured a much-anticipated update on a groundbreaking clinical trial launched in January to assess the safety and feasibility of injecting fetal stem cells into the spinal cords of people with Amyotrophic Lateral Sclerosis (ALS). To describe injecting a million cells into the precise area of the spinal…Read more

Fireside chat with Jim Till and Janet Rossant

Author: Stem Cell Network, 10/04/10

What happens when two great scientists sit down for a one-on-one to talk about their work, their mentors and what motivates them? Yes, you get some great chemistry, but more than that, you get a fascinating look at the people and process behind the identification of stem cells and the first mouse grown in the…Read more

Is 2010 the year of the stem cell Nobel?

Author: Stem Cell Network, 10/01/10

For the second year running, mainstream media in Canada and abroad has picked up on Nobel buzz surrounding stem cell scientists James Till and Ernest McCulloch, both Senior Scientists at the Ontario Cancer Institute in Toronto. Speculation surrounding a Nobel prize can be traced back to 2005, when the pair were awarded the Lasker Prize,…Read more