Archive for January, 2012

Good news for hESC trials: transplanted human embryonic stem cell-derived retinal pigment epithelium… and it’s safe!

Author: Angela C. H. McDonald, 01/26/12

As has been reported broadly this week, transplantation of human embryonic stem cell-derived retinal pigment epithelial cells appears to be safe in human patients, and it may even be efficacious (although this can only be confirmed via a Phase II trial). Advanced Cell Technology (of California) published a preliminary clinical report of their Phase I…Read more

The “Viagra effect”: how known drugs can be repurposed to target cancer stem cells

Author: Paul Krzyzanowski, 01/24/12

Repurposing known drugs for new applications is a strategy with fascinating potential, with two of the most notable examples being Thalidomide and Viagra. Thalidomide was commonly used in the late 1950s as a sedative in pregnant women, later being associated with serious birth defects. Today, it is used to treat multiple myeloma. Viagra was being…Read more

Trading on hope: A look at what motivates stem cell tourists and what happens when it goes wrong

Author: Stem Cell Network, 01/17/12

In recent years, the research community has been quite outspoken in its condemnation of rogue stem cell clinics operating in many countries across the globe. Indeed, through announcements made by health and related ministries in China, India and the US, it appears the message is beginning to be heard. On the heels of a recent…Read more

Exercising caution over unproven therapies: India holds public consultation meetings to update stem cell guidelines

Author: David Kent, 01/12/12

Last fall, I wrote on the Eurostemcell documentary film entitled Stem Cell Revolutions: A Vision of the Future, which featured some experimental stem cell treatments in India, and since that time, I have tried to keep my finger on the pulse of what has been happening in India with respect to stem cell therapy. Last month a…Read more

Sifting through all that monkey business

Author: David Kent, 01/06/12

Yesterday, a landmark paper emerged from Cell which reported two major findings to the scientific community: Primate embryonic stem cells cannot generate chimeras, and Aggregation and injection of multiple early-stage four-cell primate embryos (not embryonic stem cells) can form chimeras. Together these findings underscore a fundamental difference between rodent and primate embryonic stem cell lines…Read more