Archive for June, 2015

ISSCR 2015 Stockholm, Day 2: The air we breathe – stem cells care too.

Author: David Kent, 06/29/15

. Over the last decade, there has been a lot of talk about how blood stem cells typically live in a low oxygen environment (~1 to 4%) and most of the work that researchers do is performed at normal oxygen levels (e.g., 20% of the air). However, very few researchers have studied this in a…Read more

ISSCR 2015 Stockholm Day 1: RM – learn from nature’s masters…

Author: David Kent, 06/26/15

. I just sat through one of the simplest and most logical talks. Dr. Elly Tanaka, from Heidelberg, took the stage in the plenary session and described an incredible set of data that her lab has generated to understand the molecules involved in limb regeneration – a longstanding dream of the regenerative medicine field. Dr….Read more

Right Turn: Scaling up blood stem cells for transplants

Author: Stacey Johnson, 06/26/15

. Cord blood banking is a growing market in North America and globally. Between 2005 and 2013, the number of privately banked units grew steadily at a CAGR (compound annual growth rate) of 25 per cent, giving companies the ability to capitalize on a part of the anatomy – the umbilical cord – that has…Read more

Update from the Clinic: May

Author: Mark Curtis, 06/24/15

. Welcome to your Update from the Clinic for the month of May. StemCells announced positive topline results from a Phase I/II study in spinal cord injury. Kite Pharma treated its first patient in a Phase I/II study investigating an anti-CD19 CAR T construct in Non-Hodgkin’s Lymphoma. Following some promising interim results, NewLink Genetics decided…Read more

Regenerative Medicine Deal Review: May

Author: Mark Curtis, 06/22/15

. Welcome to your deal review for the month of May. Juno Therapeutics was active, forming a strategic research collaboration with Fate Therapeutics and acquiring Stage Cell Therapeutics. Adaptimmune decided it would take advantage of the ongoing initial public offering (IPO) window and went public to raise net proceeds of just under $180 million*. NeoStem…Read more

Right Turn: Moving RM discoveries to the market, in Ontario

Author: Stacey Johnson, 06/19/15

.Today is a big day for the regenerative medicine (RM) community in Ontario, Canada. Minister of Research and Innovation, Reza Moridi, just announced that the Ontario Institute for Regenerative Medicine (OIRM) will receive a new $25 million commitment* (in addition to the $3.1 million committed in November 2014) to invest in translational research for degenerative…Read more

Stem cell videos – who are they made for? I need reader help…

Author: David Kent, 06/16/15

. Last week the German Stem Cell Network (SCN) released three videos on the current and future possibilities of stem cells. The videos feature three top tier scientists in the field – Andreas Trumpp, Magdalena Gotz and Anthony Ho – and treat viewers to their viewpoints on where stem cell research currently sits and where it is…Read more

Right Turn: 3D prosthetics provide a helping hand

Author: Stacey Johnson, 06/12/15

. Anthony Atala MD, of Wake Forest University, is a pioneer in the field of regenerative medicine and recognized for his trailblazing and visionary work in tissue engineering and building printable organs. Signals has somehow missed out on featuring his work, despite acknowledging the efforts of other researchers in printing 3D organs here and here….Read more

‘Smart bandage’ for timely detection of bedsores

Author: Hamideh Emrani, 06/08/15

. Some of my fond memories of childhood are from the times that my great grandma and grandpa visited us. They told us sweet stories and shared memories of much simpler times. But they had worries too. I vividly remember that one of my great grandmother’s main fears was to live to an old age,…Read more

Right Turn: Making stem cells Crystal clear in TEDx talk

Author: Stacey Johnson, 06/05/15

. Crystal Ruff is a Canadian regenerative neuroscience researcher who appears to have a fondness for stem cells, communicating science and London, England (not necessarily in that order). She studied at the undergraduate level at McMaster University in Hamilton, Ontario, then went overseas to complete her PhD at University College London, then it was back…Read more