David Kent

David Kent holds a PhD in Genetics (UBC) and a BSc in Genetics and English (UWO) and is currently a CIHR postdoctoral fellow at the University of Cambridge, UK. He studies normal and malignant stem cell biology and currently sits on the executive for the Canadian Association of Postdoctoral Scholars. He also maintains his own blog for early career researchers at University Affairs, called the Black Hole (http://www.universityaffairs.ca/the-black-hole/).

Posts by: David


The importance of unequal division in stem cells

Author: David Kent, 04/30/13

. Stem cells must strike a balance between different types of divisional outcomes in order to provide the correct numbers and types of cells for the lifetime of an organism. At each cell division, a stem cell either makes two replicates of itself to expand the population (a self-renewal division), makes two highly proliferating cells…Read more

Managing energy during hibernation: Stem cell metabolome profiling

Author: David Kent, 02/08/13

Previous posts from Angela and Michelle will have alerted readers to the importance of where a stem cell resides in the body. The stem cell niche is a complicated environment and one of the most challenging things for blood stem cell biologists to decipher is how “dormant” stem cells manage their energy in such an…Read more

Pleasantly surprised at World Stem Cells congress

Author: David Kent, 05/24/12

As a basic researcher in stem cell biology, one of my biggest fears is moving too quickly with cell therapies that involve primitive, still largely mysterious, cell populations. At the World Stem Cells & Regenerative Medicine Congress meeting this week, I felt much better about the direction that regenerative medicine is headed. It has been…Read more

Strategies to boost regenerative medicine: Growing an extra layer of skin

Author: David Kent, 05/22/12

You might expect this article to be about creating skin grafts for burn victims or something of that ilk. Instead though, it concerns the complicated process of taking a scientific discovery in regenerative medicine and bringing that discovery through clinical trials or commercialization to help people. If you imagine the middle of an onion as…Read more

View from the floor 5: Pushing the boundaries with technology

Author: David Kent, 05/08/12

  The final day of the 2012 Till and McCulloch Meetings was packed with great science, but a common theme definitely emerged – technological advances are changing the way we think about and perform scientific research. Keynote speaker Helen Blau issued a warning about trying to mimic the stem cell niche outside the body, using an entertaining…Read more

View from the floor 3: Till & McCulloch Meetings

Author: David Kent, 05/02/12

  Anticipatory ethics and the problem of expectations One of my favorite things about Canadian Stem Cell Network meetings (now renamed the Till and McCulloch Meetings) is the integration into the main programming of Ethical, Legal, and Social Issues (ELSI). It forces scientists to think outside of their own research and gives ELSI researchers exposure to the…Read more

Breakfast in the shire: How is the UK reacting to Brüstle v Greenpeace?

Author: David Kent, 02/29/12

Last week I attended a breakfast at Eversheds, a law firm in Cambridge entitled Stem cell patenting, Brüstle v Greenpeace: business breaker or business as usual? which focused on the practical implications of the recent decision from the Court of Justice of the European Union on human embryonic stem (ES) cells. The event organizer, Adrian…Read more

Exercising caution over unproven therapies: India holds public consultation meetings to update stem cell guidelines

Author: David Kent, 01/12/12

Last fall, I wrote on the Eurostemcell documentary film entitled Stem Cell Revolutions: A Vision of the Future, which featured some experimental stem cell treatments in India, and since that time, I have tried to keep my finger on the pulse of what has been happening in India with respect to stem cell therapy. Last month a…Read more

Sifting through all that monkey business

Author: David Kent, 01/06/12

Yesterday, a landmark paper emerged from Cell which reported two major findings to the scientific community: Primate embryonic stem cells cannot generate chimeras, and Aggregation and injection of multiple early-stage four-cell primate embryos (not embryonic stem cells) can form chimeras. Together these findings underscore a fundamental difference between rodent and primate embryonic stem cell lines…Read more

Tick, tock, clock – the clock is ticking for you

Author: David Kent, 12/06/11

From the depths of the poetic frivolity of Raphael de la Ghetto come some words that might help guide us through one of the most interesting concepts being pursued by stem cell biologists these days.  Specifically, research has emerged which links stem cell behaviour and fate choices to circadian rhythm. The group of Salvador Aznar…Read more