Archive for the ‘clinical translation’ Category

The making of a bioactive “tissue paper”

Author: Hamideh Emrani, 09/06/17

If you live in Toronto (Canada), you know that we have two seasons: winter and construction season. Between new condo developments and homes being renovated or restored, construction is everywhere. Right now, there are five active projects going on in the relatively small neighborhood where I live! I’m annoyed by the traffic delays and noise…Read more

Right Turn: Small device packs big potential

Author: Stacey Johnson, 08/11/17

Whenever something sounds too good to be true, it usually is. The expression is used widely in a variety of contexts, one of which is as a warning to avoid being taken in by a scam or taken advantage of. Unfortunately, it applies to the stem cell field too. I am tempted to state that…Read more

Improving our understanding of how aging happens

Author: Stacey Johnson, 08/03/17

Dr. William Stanford, The Ottawa Hospital, is working with colleagues to help patients with Hutchinson-Gilford progeria syndrome (HGPS). They have shown that cells from individuals with HGPS – also called progeria – can be genetically reprogrammed, turning them into stem cells that don’t show any signs of aging. According to the news release issued by…Read more

What time zone is your heart tissue In?

Author: Holly Wobma, 06/19/17

Our lives our governed by our concept of time. Whether you are relatively spontaneous or a micromanager of your daily schedule, how we coordinate our work and interactions with other people comes down to the 24-hour clock we picture in our minds. Of course, this 24-hour clock is more than just a social construct. It…Read more

The “immunity saboteurs ” – otherwise known as T-cells

Author: Hamideh Emrani, 06/07/17

Did you know that a healthy person with a healthy lifestyle and diet might still end up being diabetic? That is certainly the case with those who have type 1 diabetes (T1D). In T1D, the patient’s body has lost the ability to produce insulin. Insulin is a hormone that acts like an agent and takes…Read more

Right Turn: Stem cell “gun” for wound healing

Author: Stacey Johnson, 06/02/17

It has been said that the pen is mightier than the sword. Where, then, does the gun factor in? I was amazed, last year, when I learned of the “biopen,” a medical device that draws stem cells to repair damaged or worn cartilage and then the cartilage heals itself with its own cells. From what…Read more

Five regenerative medicine workshops to attend this summer

Author: Guest, 05/15/17

Amin Adibi is a biomedical engineer and a health data analyst at the University of British Columbia. His areas of interest include cell manufacturing and bioprocess optimization, clinical translation of cellular therapies, health outcomes and cost-effectiveness modelling. Amin has an MSc degree from University of Calgary, where he focused on developing adjuvant MSC-based therapies for…Read more

Filling the void: A scientist’s introduction to commercialization/clinical translation

Author: Holly Wobma, 04/26/17

For anybody who has invested a great deal of time into a research project, you probably feel a certain sense of expertise on the topic. Sure, it is impossible to know a whole field (every answer raises more questions), and lab work is rife with puzzlement and failures, but at the end of the day,…Read more

The long slog of medical R&D and finding inspiration

Author: Elizabeth Csaszar, 03/27/17

Research and development (R&D) of a medical therapeutic is a long slog. This isn’t news to anyone working in the field. The average time to bring a new drug product to market is over a decade. Moreover, this is the timeline when everything progresses well – funding and business decisions align, manufacturing processes come together,…Read more

From organ survival to organ revival – how patients can regenerate their own donor lung prior to surgery

Author: Holly Wobma, 03/22/17

For most areas of medicine, the supply of a treatment can easily meet demand (access issues aside). Need an antibody? A steroid? Millions of pills are manufactured every day. The case could not be more different for solid organ transplantation, for which the list of patients with end-stage organ failure vastly exceeds the number of…Read more