Archive for the ‘clinical translation’ Category

The long slog of medical R&D and finding inspiration

Author: Elizabeth Csaszar, 03/27/17

Research and development (R&D) of a medical therapeutic is a long slog. This isn’t news to anyone working in the field. The average time to bring a new drug product to market is over a decade. Moreover, this is the timeline when everything progresses well – funding and business decisions align, manufacturing processes come together,…Read more

From organ survival to organ revival – how patients can regenerate their own donor lung prior to surgery

Author: Holly Wobma, 03/22/17

For most areas of medicine, the supply of a treatment can easily meet demand (access issues aside). Need an antibody? A steroid? Millions of pills are manufactured every day. The case could not be more different for solid organ transplantation, for which the list of patients with end-stage organ failure vastly exceeds the number of…Read more

Improving ultrasound imaging may have applications in regenerative medicine

Author: Guest, 03/13/17

Andy Bell, a writer working with Toronto3dprinting, loves to write about different topics related to technological gadgets and gears. 3D printing is his current interest. Though ultrasound technology is commonly associated with the imaging of fetuses in the womb, its applications are much more than just imaging. The acoustic waves generated by ultrasound devices can…Read more

Learning About Industry from the Insiders at Phacilitate Cell and Gene Therapy World 2017

Author: Nicole Forgione, 02/08/17

In January, I attended Phacilitate’s Cell and Gene Therapy World in Miami, Florida. At this meeting industry leaders from around the world gather to discuss manufacturing, regulation and adoption of cell and gene therapies (C&GT). This was my first industry-focused conference, and it was a great chance to learn the ropes from experienced players in…Read more

Can we use animals as living incubators for human tissue?

Author: Jovana Drinjakovic, 01/16/17

Markus Grompe certainly thinks so and is working hard to make it happen. A scientist and a pediatrician specializing in inborn liver diseases, Dr. Grompe has a plan for overcoming the shortage of organ donors—the key obstacle for patients for whom the liver transplant is the only hope. Based at the Oregon Health and Science…Read more

A credit card sized lab

Author: Hamideh Emrani, 12/29/16

Professor Aaron Wheeler earned his PhD from Stanford University and, after a two-year postdoc fellowship at UCLA, joined the faculty of Chemistry at the University of Toronto. He has won numerous awards and honours for his work in the field of microfluidics and is the associate editor of Lab on a Chip. Wheeler’s lab develops…Read more

Right Turn: These three videos show why we should be impressed by our young stem cell researchers

Author: Lisa Willemse, 11/18/16

Stroke, lung damage and mathematical modeling. You may not think these three topics have much in common and for the most part you’d be right. But they have more than one common link. First, each is either a disease focus or methodology within stem cell research. Secondly, each subject –biomaterials to aid stem cell engraftment…Read more

Insights from CGTW16 – Part 1: Cell Manufacturing Best Practices

Author: Guest, 11/17/16

Amin Adibi is a biomedical engineer and a research assistant at the University of British Columbia. His areas of interest include cell manufacturing and bioprocess optimization, clinical translation of cellular therapies, health outcomes and cost-effectiveness modelling. Amin has an MSc degree from University of Calgary, where he focused on developing adjuvant MSC-based therapies for brain…Read more

A peek into a septic shock clinical trial and a patient’s message of hope (TMM2016-Day2)

Author: Hamideh Emrani, 10/27/16

The second day of the Till & McCulloch Meetings (TMM) kicked off with a great talk by Dr. Masayo Takahashi of the Riken Center for Developmental Biology, on the generation of retinal progeny and photoreceptors from iPSCs and ESCs. However, for today, I would like to focus on two different talks. I am sure further…Read more

Rewarding Excellence – Awardees at TMM2016

Author: Camila Londono, 10/26/16

The feature session of the fifth Till & McCulloch Meetings shone a light on two fantastic researchers, Huijuan Yang and Molly Shoichet, both of whom received awards for their outstanding work. Huijuan Yang, a PhD student in the Nagy lab at the Lunenfeld-Tanenbaum Research Institute at Mount Sinai hospital in Toronto, received the inaugural Drew…Read more