Archive for the ‘Clinical trials’ Category

Why do stroke regenerative therapies fail to reach the clinic?

Author: Samantha Payne, 03/07/17

The author of the popular Seven Habits of Highly Effective People book, Steven R. Covery, said “strength lies in differences, not in similarities.” While this may be helpful advice for improving your personal life, researchers are learning that differences in preclinical studies are weakening the ability to translate effective therapies to the clinic. While one…Read more

Learning About Industry from the Insiders at Phacilitate Cell and Gene Therapy World 2017

Author: Nicole Forgione, 02/08/17

In January, I attended Phacilitate’s Cell and Gene Therapy World in Miami, Florida. At this meeting industry leaders from around the world gather to discuss manufacturing, regulation and adoption of cell and gene therapies (C&GT). This was my first industry-focused conference, and it was a great chance to learn the ropes from experienced players in…Read more

Wave of the future: Using anesthesia to detect neurodegeneration

Author: Samantha Payne, 01/03/17

Most people have experienced being put to sleep for a surgical procedure, whether it is relatively minor like the removal of a tooth, or major heart surgery. In fact, every day 60 000 people will undergo general anesthesia in the U.S. You may have noticed a lot of stories sound similar: “I was completely awake…Read more

Crazy for CRISPR!

Author: Sara M. Nolte, 12/05/16

On November 15th, my social media pages exploded with posts and comments regarding the latest news about how the gene-editing ‘CRISPR-Cas9’ technology had been used in the first human patient. The article, published by Nature, was entitled “CRISPR gene-editing tested in a person for the first time.” It described how a group of Chinese scientists…Read more

Insights from CGTW16 – Part 3: Clinical trials, health economics and regulatory affairs

Author: Guest, 12/01/16

Amin Adibi is a biomedical engineer and a research assistant at the University of British Columbia. His areas of interest include cell manufacturing and bioprocess optimization, clinical translation of cellular therapies, health outcomes and cost-effectiveness modelling. Amin has an MSc degree from University of Calgary, where he focused on developing adjuvant MSC-based therapies for brain…Read more

Right Turn: The story of scurvy is a poignant cautionary tale for modern medical science

Author: Guest, 11/04/16

Elizabeth (Liz) Csaszar is a development manager for the BridGE team at CCRM. Her areas of interest are cell manufacturing, clinical translation of cell based therapies, and blood cell technologies. Liz obtained her PhD at the University of Toronto, focusing on the strategies to expand and self-renew hematopoietic stem cells in vitro. Liz is interested in…Read more

A peek into a septic shock clinical trial and a patient’s message of hope (TMM2016-Day2)

Author: Hamideh Emrani, 10/27/16

The second day of the Till & McCulloch Meetings (TMM) kicked off with a great talk by Dr. Masayo Takahashi of the Riken Center for Developmental Biology, on the generation of retinal progeny and photoreceptors from iPSCs and ESCs. However, for today, I would like to focus on two different talks. I am sure further…Read more

Right Turn: Finding a treatment for vision loss is looking up

Author: Stacey Johnson, 10/21/16

October 13, 2016 was World Sight Day and the month of October is dedicated to blindness and vision loss awareness. No doubt that is why the California Institute for Regenerative Medicine (CIRM) recently shared the third installment in its Stem Cells in Your Face series. In the video below, narrator Kevin McCormack, whose day job…Read more

Right Turn: Hope for patients suffering from sepsis

Author: Stacey Johnson, 09/16/16

September is Sepsis Awareness Month and World Sepsis Day was acknowledged earlier this week – on Tuesday, September 13. That’s why there’s a good possibility that you have seen the video below, about a heartbroken mother who lost her young son to sepsis. (It has already been viewed millions of times.) Her grief is real…Read more

The stem cell therapy’s obstacle course

Author: Jovana Drinjakovic, 08/25/16

Science fiction became real life in September 2014, when a team of eye surgeons in Japan transplanted a body part, grown entirely in a dish, into the eye of a patient suffering from an eye disease. The retinal graft came from the patient’s skin cells, raising hopes that one day our own bodies could be…Read more