Archive for the ‘Research’ Category

The making of a bioactive “tissue paper”

Author: Hamideh Emrani, 09/06/17

If you live in Toronto (Canada), you know that we have two seasons: winter and construction season. Between new condo developments and homes being renovated or restored, construction is everywhere. Right now, there are five active projects going on in the relatively small neighborhood where I live! I’m annoyed by the traffic delays and noise…Read more

Improving our understanding of how aging happens

Author: Stacey Johnson, 08/03/17

Dr. William Stanford, The Ottawa Hospital, is working with colleagues to help patients with Hutchinson-Gilford progeria syndrome (HGPS). They have shown that cells from individuals with HGPS – also called progeria – can be genetically reprogrammed, turning them into stem cells that don’t show any signs of aging. According to the news release issued by…Read more

Relay race to finish off inflammatory cells

Author: Holly Wobma, 07/12/17

I don’t have many distinct memories from childhood. Certainly not of global events. But given the sweltering weather, the recent Canada 150 celebration, and a cool new paper published in Cell Chemical Biology, my mind wandered back to the ’96 summer Olympics (Atlanta), when Donovan Bailey raced through the finish line with his arms in…Read more

Location, location, location – stem cells need the right neighbours

Author: David Kent, 06/12/17

Last month two papers created a pretty big wave in the blood stem cell field: Work from Harvard Medical School and Cornell University showed that functional human blood stem cells could be created from reprogrammed cells. While it is most certainly the closest that researchers have come to creating blood stem cells in large numbers…Read more

The “immunity saboteurs ” – otherwise known as T-cells

Author: Hamideh Emrani, 06/07/17

Did you know that a healthy person with a healthy lifestyle and diet might still end up being diabetic? That is certainly the case with those who have type 1 diabetes (T1D). In T1D, the patient’s body has lost the ability to produce insulin. Insulin is a hormone that acts like an agent and takes…Read more

Enabling technologies are helping regenerative medicine to succeed

Author: Stacey Johnson, 04/11/17

Earlier this year, the University of Toronto’s Institute of Biomaterials and Biomedical Engineering (IBBME) published its Annual Report, chock full of impressive numbers about enrolment, new programs and research published by its esteemed faculty. (If you’re curious, you can read it for yourself.) In response, I summarized the regenerative medicine research here. But I only…Read more

A peek at exciting research happening at the University of Toronto

Author: Stacey Johnson, 01/25/17

CCRM has been known to hire its graduates, consult with its esteemed professors, review disclosures from its faculty, collaborate on projects, and our Chief Scientific Officer, Dr. Peter Zandstra, is one of its respected professors. All of this to disclose that CCRM has very strong ties to the Institute of Biomaterials and Biomedical Engineering (IBBME)…Read more

Can we use animals as living incubators for human tissue?

Author: Jovana Drinjakovic, 01/16/17

Markus Grompe certainly thinks so and is working hard to make it happen. A scientist and a pediatrician specializing in inborn liver diseases, Dr. Grompe has a plan for overcoming the shortage of organ donors—the key obstacle for patients for whom the liver transplant is the only hope. Based at the Oregon Health and Science…Read more

Making a case for research investment in Canada: Can we drive reverse brain drain now?

Author: Camila Londono, 01/11/17

Brain drain was a real problem for Canada in the late ‘90s. A study by Statistics Canada found that twice as many post-secondary professors and teachers went to the United States than came to Canada in that period. This untenable situation—in which education and infrastructure investments in people were lost through decreased funding, higher taxes…Read more

Crazy for CRISPR!

Author: Sara M. Nolte, 12/05/16

On November 15th, my social media pages exploded with posts and comments regarding the latest news about how the gene-editing ‘CRISPR-Cas9’ technology had been used in the first human patient. The article, published by Nature, was entitled “CRISPR gene-editing tested in a person for the first time.” It described how a group of Chinese scientists…Read more