More ISSCR meeting insights from James Ellis of Toronto’s Hospital for Sick Children and Michael Rudnicki, Scientific Director of the Stem Cell Network.
More thoughts on the ISSCR conference in San Francisco from the attendees.
We’re a the ISSCR meeting in San Francisco inviting folks to stop by the Stem Cell Network booth (number 509), sit on our comfy couch and talk about what they’ve enjoyed the most at the 2010 ISSCR annual meeting. Featured here are Bernard Thébaud of the University of Alberta and Rebecca Skinner of the Australian Stem…Read more
How do adult stem cells work? In healthy tissue the adult stem cell population lies dormant. Dormant stem cells are activated by external trauma signals, which trigger patterns of gene expression and protein biosynthesis, thus activating the stem cells to multiply and regenerate damaged tissue. If you think of your normal tissue as a car,…Read more
Simple diagram that shows the development of different blood cells from hematopoietic stem cell to mature cells. From Wikipedia. All blood cells arise from the common hematopoietic stem cell and are classified into two lineages: lymphoid cells (B-, T- and Natural Killer [NK] cells) which play an important role in adaptive and innate immune response,…Read more
When using stem cells for regenerative therapies, there are a few approaches that can be taken. Donor cells have issues with matching and immune rejection. Autologous stem cells transplants skirt rejection issues, but both strategies still face challenges associated with the ex vivo expansion of cells, such as culture consistency and the need for better…Read more
The UK-based Motor Neurone Disease Association has recently funded a £800,000 ($1.2 million) program to study motor neurons derived from the skin cells of amyotrophic lateral sclerosis (ALS) patients with rare, disease-causing mutations in the gene TARBP. Although the mutations are thought to cause only a tiny fraction of cases, abnormalities in the gene’s protein…Read more
Part one in a series looking at the processes involved in the most clinically applied form of stem cell therapy: hematopoietic stem cell transplantation Leukocytes, or white blood cells (WBCs), are an essential part of the immune system. Produced in the bone marrow, healthy WBCs protect the body against infection and pathogens. Cancers such as…Read more
The potential gains from stem cell research are unlimited; stem cells could be used to replace degenerated cells and tissue in the human body. However, the large scale implementation of stem cell therapy to a clinical setting will require the establishment of a reliable and controllable method of expanding and differentiating the cells. While one…Read more