Launch of the International Stem Cell Registry

Author: Stem Cell Network, 08/12/09

The mission of the University of Massachusetts International Stem Cell Registry is to provide a searchable, comprehensive database that includes published and validated unpublished information on all human embryonic (hESC) and induced pluripotent (iPS) stem cell lines. The goal is to offer current information on all known human pluripotent cell lines, including those approved by the National Institutes of…Read more

How similar are mast cells and hematopoietic stem cells?

Author: Stem Cell Network, 08/07/09

Mast cells are cells of the immune system that play a role in inflammatory responses, such as allergies and asthma. They share a number of surface markers (“identifier” molecules on a cell that help scientists distinguish between different types of cells) with hematopoietic stem cells (HSCs). The similarity in these surface markers between mast cells…Read more

A new model to expand blood stem cells

Author: Stem Cell Network, 07/31/09

In a Molecular Systems Biology paper released this week, our team at the University of Toronto revealed a new mathematical model that links functional cellular assays to specific model outputs, defines cell-level kinetic parameters such as cell cycle rates and self-renewal probabilities as functions of culture variables, and simulates feedback regulation using cell–cell interaction networks….Read more

Canadian stem cell researchers Eaves and Dick to receive hematology awards

Author: Michael Rudnicki, 07/31/09

The American Society of Hematology recently announced six award recipients to be honoured for their outstanding scientific contributions in the field of hematology. Among the distinguished scientists who are to receive awards are two Canadians – Connie Eaves and John Dick – both of whom are Stem Cell Network researchers. I am very proud of…Read more

Mending broken hearts

Author: Stem Cell Network, 07/29/09

Cardiovascular disease accounts for the death of more Canadians than any other disease, more than 72,000 people each year. There is currently no cure for heart failure, and goals for treatment have always been to improve symptoms, stop the condition from getting worse, and prolong life span. But results from recent stem cell trials point…Read more

Updates on MS, stroke, spinal cord injury and more

Author: Stem Cell Network, 07/24/09

New research in the area of regenerative medicine is coming out regularly.  Here are some recent examples: Researchers in Toronto and Saskatchewan are looking at cells found in human skin, inside the nose and in the spinal cord as autologous sources of myelinating cells to treat multiple sclerosis. A UK company called ReNeuron is starting…Read more

ISSCR 2009: outside the plenary hall

Author: Stem Cell Network, 07/13/09

Cel-lules mare – The night before ISSCR’s 7th Annual Meeting officially began, a public symposium was held at CosmoCaixa Barcelona in the north end of the city.  The event was open to everyone attending ISSCR as well as curious members of the Spanish public. The evening started with ESTOOLS’ “Smile of a Stem Cell” photo…Read more

Muscle repair enhanced by stem cells: new research

Author: Michael Rudnicki, 06/05/09

In a Cell Stem Cell paper released today, my team at the Ottawa Hospital Research Institute demonstrated how the Wnt7a protein, signaling through the planar cell polarity pathway, controls the homeostatic levels of stem cells in muscle tissue, generating close to a 20% increase in the size of the tissue. In lay terms, this means we…Read more

Stepping forward in genomics and biomedical research

Author: Michael Rudnicki, 05/08/09

The word out of Ontario has been very positive of late. Despite the difficult financial times, the 2009-2010 provincial budget contained a number of new measures including: $300 million in new capital funds over six years for research infrastructure to be leveraged against the federal Canada Foundation for Innovation, $250 million over five years for…Read more