Posts Tagged ‘cancer’

Guardian of the genome goes rogue in cultured stem cells

Author: Jovana Drinjakovic, 05/10/17

Last month, a study published in Nature revealed that researchers have unknowingly been working on human stem cell lines that harbour mutations in a gene linked to many cancers, raising safety concerns over their use in therapy. But the findings don’t condemn stem cell treatment to an early grave. Instead, they raise an awareness of…Read more

Enabling technologies are helping regenerative medicine to succeed

Author: Stacey Johnson, 04/11/17

Earlier this year, the University of Toronto’s Institute of Biomaterials and Biomedical Engineering (IBBME) published its Annual Report, chock full of impressive numbers about enrolment, new programs and research published by its esteemed faculty. (If you’re curious, you can read it for yourself.) In response, I summarized the regenerative medicine research here. But I only…Read more

Right Turn: Checking in on Research2Reality

Author: Stacey Johnson, 02/17/17

Research2Reality will soon be celebrating its 2nd anniversary. I first wrote about it when it launched and was excited by its mission to highlight the work of scientists across Canada, from a variety of disciplines, and make their research interesting and understandable to a non-expert audience. Through videos and blogs, Research2Reality is “shining a light…Read more

Cells…in a box

Author: Guest, 02/13/17

Heather Blumenthal has been writing about health and health research for more than 20 years and never loses her fascination with the advances Canadian researchers are making. You can reach her at hblumenthal@sympatico.ca It’s like magic – insert a cancer patient’s blood cells in one end and out the other end come T-cells adapted for…Read more

Sculpted to a T: Synthetic T-cells for a more controlled immune response

Author: Holly Wobma, 10/18/16

I have a confession.  This is not a blog about stem cells. It is, however, a blog about cells with infinite possibilities of fate. Because we are entering the world of synthetic biology, where crafty cellular engineering has enabled a new level of control over immune cell function. This work comes out of Wendell Lim’s…Read more

ISSCR final day – Not just one hit… finding combinations in cancer

Author: David Kent, 07/18/16

During the morning plenary session on the final day of ISSCR, we were treated to a delightful mix of basic and translational science as well as a riveting public policy lecture from Alta Charo. The session was all about disease modeling and stem cells and the highlight talk for me was from Guy Sauvageau, who…Read more

Cell Therapy Deal Review: March

Author: Mark Curtis, 04/25/16

Welcome to your Cell Therapy Deal Review for the month of March. Cellectis continues to differentiate through a collaboration with MabQuest. PCT formed a partnership with Japanese conglomerate Hitachi. Kite partnered with Roche’s Genentech on a program for lymphoma. Cellectis (CLLS) has already separated itself from the pack with UCART19, a universal CAR product targeting…Read more

Update from the Clinic: January

Author: Mark Curtis, 02/22/16

Welcome to your update from the clinic for the month of January. It was a quiet month in the clinic. However, we did see some clearances for various clinical studies, including Fate’s ProTmune in GvHD and Pluristem’s PLX-R18 in hematopoietic recovery following bone marrow transplant. Pluristem (PSTM) continues to increase the breadth of applications for…Read more

Cell Therapy Deal Review: January

Author: Mark Curtis, 02/18/16

Welcome to your Cell Therapy Deal Review for the month of January. Things got off to a quick start with a number of cell-based immunotherapy companies announcing deals and research collaborations out of the gate, including a third acquisition by Juno. Juno Therapeutics (JUNO) brought further depth to its research & discovery platform through the…Read more

Right Turn: An estimated 22,465 people died from cancer yesterday

Author: Stacey Johnson, 02/05/16

According to the World Health Organization, there were 8.2 million cancer related deaths in 2012 so by my calculations, that’s over 22,000 each day. Cancer has been on my mind a lot this week, and not just because yesterday was #WorldCancerDay. On February 1st, the wife of a friend passed away from leukaemia. She had…Read more