Posts Tagged ‘iPS’

StemCellShorts 3: What are induced pluripotent stem cells?

Author: Ben Paylor, 10/25/13

“Canada is home to numerous stem cell discoveries and StemCellShorts is an excellent medium through which we can convey these accomplishments to Canadians and others worldwide.  The ‘shorts’ are innovative, educational and entertaining”.  — Dr. Mick Bhatia, Director and Senior Scientist at the McMaster Stem Cell and Cancer Research Institute, and Canada Research Chair in Human…Read more

Jailbreaking cell fate reprograms to multiple stem cell types says Nagy

Author: Guest, 10/24/13

Guest post by Paul Knoepfler, cross-posted on You can jailbreak your iPhone, but perhaps you can jailbreak a cell too to turn it into a stem cell. In his very cool talk up here at the Till & McCulloch Meeting on Stem Cells yesterday, Andras Nagy characterized the reprogramming process to make iPS cells as “jailbreaking”…Read more

Day 1 at #TMM2013: Hongkui Deng breaks down iPS cells

Author: David Kent, 10/23/13

> Set in the beautiful mountain setting of Banff National Park, the first hours of the Till and McCulloch meeting have not disappointed. Our morning plenary began with an excellent historical perspective from Shin-Ichi Nishikawa on the origins of blood stem cells and rolled on through an excellent series of talks on epigenetic regulation and…Read more

Jacob Hanna on Radically Deterministic Reprogramming @TMM2013

Author: Guest, 10/23/13

Guest post by Paul Knoepfler, cross-posted on What is “radically deterministic” cellular reprogramming? Jacob Hanna’s lab recently published a very high profile Nature paper on nearly 100% efficient iPS cell formation based on targeting a factor called Mbd3. This super efficiency is a major departure from past reported efficiencies. This morning here at the…Read more

Right Turn: The next top model is in a dish

Author: Lisa Willemse, 08/02/13

. Studying disease in a petri dish is nothing new. But the way we’ve been able to make models of disease – and turn those diseased cells back in time to their earliest beginnings – is new. By peering back in time, researchers are gathering a wealth of new information about how diseases originate and…Read more

From Japan with love: Cell therapy intellectual property prospects

Author: David Brindley, 07/09/13

. At the close of ISSCR2013, I left Boston bathed in an ochre sunset, and settled on a plane to reflect on what my most unexpected learning had been. My plane was bound not for home (London), but for Istanbul, where the TERMIS meeting was about to begin. As far as I’m aware, the last…Read more

Using stem cells to cure… extinction?

Author: Peter Raaymakers, 05/15/13

In last week’s Right Turn, we talked about how stem cells are responsible for the colours and patterns of bird feathers—and birds, as the graphic on the right demonstrates, are basically just tiny dinosaurs. Given that there is much promise in stem cell research (and also a great deal of hype), it makes one wonder:…Read more

What if the game changes again? Perfect ES models in sight

Author: Paul Krzyzanowski, 11/21/12

  While the 2012 US election was in full swing, I reminded readers that despite the dominance of the world’s economic problems in this cycle, stem cell research was a political issue that hadn’t completely gone away.Methods to generate induced pluripotent stem cells (iPS cells) have constantly improved over the past few years, elegantly positioning…Read more

On nations and inflammation: How viruses can promote cellular reprogramming

Author: Holly Wobma, 11/14/12

As many of you well know, the U.S. presidential election recently came to a close. Over the last year, there have been numerous speeches from a variety of sources, some of which have been able to rally the masses, due not only to their content but also the speaker’s masterful elocution. Indeed, when it comes…Read more

The future of the stem cell controversy: Do citizens prefer iPS cells?

Author: Nick Dragojlovic, 11/08/12

If you’ve been feeling like you can’t open a web browser these days without finding a story about induced pluripotent stem cells (iPSCs), you’re not alone.  Unlike embryonic stem cells, iPSCs are created by directly reprogramming adult cells taken from donors or patients, and they’ve been all over the news. Most notably, Sir John B….Read more