Posts Tagged ‘T-cells’

Cells…in a box

Author: Guest, 02/13/17

Heather Blumenthal has been writing about health and health research for more than 20 years and never loses her fascination with the advances Canadian researchers are making. You can reach her at hblumenthal@sympatico.ca It’s like magic – insert a cancer patient’s blood cells in one end and out the other end come T-cells adapted for…Read more

Crazy for CRISPR!

Author: Sara M. Nolte, 12/05/16

On November 15th, my social media pages exploded with posts and comments regarding the latest news about how the gene-editing ‘CRISPR-Cas9’ technology had been used in the first human patient. The article, published by Nature, was entitled “CRISPR gene-editing tested in a person for the first time.” It described how a group of Chinese scientists…Read more

Sculpted to a T: Synthetic T-cells for a more controlled immune response

Author: Holly Wobma, 10/18/16

I have a confession.  This is not a blog about stem cells. It is, however, a blog about cells with infinite possibilities of fate. Because we are entering the world of synthetic biology, where crafty cellular engineering has enabled a new level of control over immune cell function. This work comes out of Wendell Lim’s…Read more

Update from the Clinic: February

Author: Mark Curtis, 03/24/16

Welcome to your Update from the Clinic for the month of February. bluebird made its debut in the oncology market and treated its first patient with a chimeric antigen receptor (CAR) product targeting a novel antigen. Ziopharm enrolled its first patient in a study investigating a non-viral CD19 CAR product, while Sangamo entered the clinic…Read more

Organ transplantation: Using biomaterials to prevent immune rejection

Author: Guest, 01/26/16

Samantha is a PhD student in the Chemical Engineering and Applied Chemistry department at the University of Toronto. She has previously investigated regeneration in a non-mammalian gecko model during an MSc program, and now currently combines stem cell biology and biomaterials to encapsulate and deliver therapeutic cells to the stroke-injured brain. Samantha became interested in…Read more

Cell Therapy Deal Review: August

Author: Mark Curtis, 09/30/15

. Welcome to your cell therapy deal review for the month of August. Synthetic biology giant Intrexon closed a large financing; Immune Design announced a collaboration to pair its viral-based immunotherapy platform with a checkpoint inhibitor; and, NantKwest received a discovery grant to investigate NeukoPlastTM in prostate cancer. In other news we saw earnings reported,…Read more

Highlights from the 2015 “Business of Regenerative Medicine” course

Author: Guest, 08/27/15

. Nadia Houri is a Business Development Analyst with the Centre for Commercialization of Regenerative Medicine (CCRM).   Last month, I had the pleasure of attending The Business of Regenerative Medicine: Cells at Work course, hosted by Georgia Tech, in Atlanta. With two and a half very full days of lectures and networking opportunities, cells…Read more

Update from the Clinic: April

Author: Mark Curtis, 05/25/15

. Welcome to your Update from the Clinic for the month of April. Mesenchymal stem cells took a hit as Athersys’ MultiStem came up short, missing its primary endpoint in a Phase 2 study investigating the cells for ischemic stroke. Juno Therapeutics continues to turn heads with its Phase 1/2 data in blood cancers. NeoStem,…Read more

Regenerative Medicine Deal Review: September

Author: Mark Curtis, 10/09/14

Welcome to your deal review for the month of September. There was some healthy news flow around cell-based immunotherapy companies this past month, heating up a space that is already ablaze with activity. Undoubtedly the company that took the spotlight was Adaptimmune, which completed a venture capital (VC) round of over $100 million! The money…Read more

Rejuvenation therapy for our aging T-cells (and what it may mean to cancer treatment)

Author: Holly Wobma, 01/10/13

It is said that with age comes “wisdom”; however, I often think that “exhaustion” might serve as a reasonable substitute. As we deal with life’s stresses, and new hairs sprout of snowy white hues, it is hard not to think of our younger days of freedom and vitality. If I could anthropomorphize a cell, I…Read more