Archive for January, 2015

Right Turn: Multiple sclerosis clinical trial begins in Ottawa

Author: Peter Raaymakers, 01/30/15

  Click image to go to CTV News Ottawa video     We’ve written about some questionable “clinical trials” recruiting patients in Canada recently, so it only makes sense to follow-up with some hopeful news about a legitimate, regulator-approved trial that launched this past week. Dr. Mark Freedman, Senior Scientist of the Neuroscience Program at the Ottawa…Read more

Travelling to another dimension: going from 2D to 3D cell culture

Author: James Smith, 01/26/15

With contributions from David Brindley . Cell-based treatments are being developed and marketed for a variety of indications: from rare orphan diseases like graft versus host disease (GvHD), to blockbuster conditions like diabetes and cardiovascular disease that affect huge numbers of people. For these conditions, assuming that the treatment is effective, generating adequate quantities of…Read more

Right Turn: Blockbuster toy or super (silly) biomaterial?

Author: Stacey Johnson, 01/23/15

. Signals’ mandate is to bring you, dear reader, blogs about stem cells, commercialization and biomaterials, but lately there hasn’t been much of the latter; therefore, I’ve decided to try to fill that gap. But before you get too excited, I am in no way an expert on biomaterials, despite my affection for them (and…Read more

Luck is on their side in “bad luck” cancer study

Author: Stacey Johnson, 01/20/15

. Before you read my blog, I recommend that you first read Sara Nolte’s blog “Bad luck, bad science, or bad reporting?” In it, Sara does an excellent job explaining and commenting on Drs. Cristian Tomasetti’s and Bert Vogelstein’s study “Variation in cancer risk among tissues can be explained by the number of stem cell…Read more

Bad luck, bad science, or bad reporting?

Author: Sara M. Nolte, 01/19/15

. If you’ve been on the Internet at all in 2015, you’ve probably stumbled across headlines like “Two-thirds of cancers are due to ‘back luck,’ study finds” (CBSNews), “Most cancers are caused by bad luck not genes or lifestyle say scientists” (The Telegraph), “Cause of cancer revealed: majority of cases down to ‘bad luck’ rather…Read more

Penalty for Regenetek – Two minutes for obfuscation

Author: Lisa Willemse, 01/16/15

> There are few things in Canada that grab national attention than a story related to hockey. News that surfaced last month that hockey legend Gordie Howe had received an unproven stem cell therapy for stroke continue to grab headlines in this country. In the past week alone, our office has fielded several media calls…Read more

Update from the Clinic: December

Author: Mark Curtis, 01/13/15

. Welcome to your Update from the Clinic for the month of December. bluebird bio’s first four patients are transfusion-free after treatment with its gene therapy Lentiglobin. Fate Therapeutics’ hematopoietic stem cell-modulating technology ProHema seems to be on track to produce results in the clinic. bluebird bio (BLUE), which recently priced a common offering to…Read more

Right Turn: Remembering the warning signs of Alzheimer’s disease

Author: Stacey Johnson, 01/09/15

. Alzheimer’s disease is a chronic, neurodegenerative disease characterized by loss of memory and changes in behaviour in the early stage. It typically starts slowly and progresses, within a decade, to death from an external factor, such as an infection or pneumonia, or the person’s body completely shuts down. According to the Alzheimer Society of…Read more

Regenerative Medicine Deal Review: December

Author: Mark Curtis, 01/07/15

. Welcome to your deal review for the month of December. Juno Therapeutics made its leap into the public realm with the largest biotech initial public offering (IPO) in 2014. bluebird Bio announced pricing of a common offering to raise over $200M. Read on to find out more. Earlier this year, we saw privately held…Read more

Right Turn: How your New Year’s Resolution works

Author: Peter Raaymakers, 01/02/15

One of the most common New Year’s Resolutions made every year: Exercise regularly and get in better shape. It’s a noble resolution, often broken, but worthwhile nonetheless. But have you ever wondered how that resolution works? Wonder no more: This great video, from EuroStemCell, explains how stem cells respond to the cues given during workouts…Read more