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Stem cells and high throughput screening

High-throughput screening, in which many cell culture conditions can be tested using a combination of robotics, control software, and/or highly sensitive detection, allows researchers to explore new ideas quickly; thousands of combinations can be efficiently tested...

Even in pharmaceuticals, it’s an RNA world

In the RNA world hypothesis, RNA based biological life can exist without the need for DNA and proteins to store information, make decisions, and in general, control cells. In 1998, the discovery that small RNAs can play important roles in controlling cells...

Ghosts of stem cells past

One of the coolest breakthroughs of the last five years is the ability to reprogram adult, differentiated cells into pluripotent cells, effectively allowing us to change one cell type into virtually any other. Reprogramming is achieved by expression of a set of genes...

iPS cells can help speed traditional drug development

Imagine that you’ve just discovered a novel drug that potentially solves a medical problem, one that accelerates wound healing in skin or can reduce the size of cancerous tumors. You can show the effects beautifully in your model tissue culture system and mice...