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Angela C. H. McDonald

Angela is a PhD student in the Stem Cell and Developmental Biology program at the Hospital for Sick Children in Toronto. She is currently utilizing pluripotent stem cells to understand the genetic regulation of endoderm development. As an avid supporter of public science education, she co-founded the high school outreach initiative StemCellTalks sits on numerous public education committees including the International Society for Stem Cell Research Public Education Committee and the Stem Cell Network Public Outreach Committee.

Posts by: Angela


Interspecies chimeras – will farm animals be regenerative medicine vehicles of the future?

Author: Angela C. H. McDonald, 06/26/12

Hiromitsu Nakauchi has a vision for regenerative medicine. In this vision, he sees a renewable source of human organs for transplantation that are grown within the bodies of farm animals. Here’s how it works: pluripotent stem cells would be injected into an early animal embryo that is not capable of generating a specific organ. As […]

One step closer to a viable cell replacement strategy for muscular dystrophy

Author: Angela C. H. McDonald, 06/07/12

Late in May, the Brampton Fire Department (just outside of Toronto) held a “boot drive” to raise money for Muscular Dystrophy.  My boyfriend who happens to be a firefighter tells me that boot drives are fairly common among Canadian fire departments.  In fact, they are often specifically supporting Muscular Dystrophy Canada.  At a boot drive, […]

Researchers use their ‘noodles’: nanotechnology for regenerative medicine

Author: Angela C. H. McDonald, 05/29/12

Nanotechnology has been a buzzword in the medical technology community for some time. It is defined as the manipulation and use of microscopic structures at the molecular scale, generally 1-100 nanometres in size (1 nanometre is 1 billionth of a metre, which translates to approximately 1 billionth the length of a baseball bat!) Nanotechnology is […]

Gene deletion to create insulin-producing cells

Author: Angela C. H. McDonald, 04/17/12

Most research on stem cells involves the manipulation of gene expression, to some degree or another. During stem cell differentiation, the expression of specific genes orchestrates the choices cells make along the path from stem cell to adult cell — a process known as differentiation. Here’s how it works: the expression (or lack thereof) of […]

Using titanium to induce bone differentiation and personalized implants

Author: Angela C. H. McDonald, 03/21/12

Titanium can be found everywhere. It is used in cars, sporting equipment and even jewelry manufacturing. But did you know that titanium products are used inside the human body? You may know someone who has undergone a joint replacement procedure or someone who has a dental implant. For decades, titanium alloys have been used as […]