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Explaining the hype: CAR T-cells

With the start of a new year, I like to take a moment to think about what things in cancer research got me really excited the previous year. Beyond a doubt, that thing for me in 2017 was the first (and second!) FDA approval of a CAR T-cell (chimeric antigen receptor...

Bioprocessing and bioanalytics

The recent FDA approvals of Kymriah™ for the treatment of children and young adults with B-cell Acute Lymphoblastic Leukemia, and Yescarta™ to treat adults with certain types of non-Hodgkin lymphoma, and the unanimous endorsement by an FDA advisory committee of a gene...

Right Turn: Unwrapping bubble boy disease

Before Jake Gyllenhaal starred in the 2001 comedy Bubble Boy, there was a 1976 version starring John Travolta called The Boy In The Plastic Bubble. Both movies were inspired by the lives of David Vetter, who had severe combined immunodeficiency (SCID), and Ted DeVita,...