Stem Cell Network
Posts by: Stem
New insights on eye stem cells
Retinal stem cells have now been created from human skin, adding yet another specialized cell type to a rapidly growing list of cells that can be created using induced pluripotent (iPS) methodology. The finding could prove to be an important method in the production of human retinal cells, which would help overcome one of the […]
Launch of the International Stem Cell Registry
The mission of the University of Massachusetts International Stem Cell Registry is to provide a searchable, comprehensive database that includes published and validated unpublished information on all human embryonic (hESC) and induced pluripotent (iPS) stem cell lines. The goal is to offer current information on all known human pluripotent cell lines, including those approved by the National Institutes of […]
How similar are mast cells and hematopoietic stem cells?
Mast cells are cells of the immune system that play a role in inflammatory responses, such as allergies and asthma. They share a number of surface markers (“identifier” molecules on a cell that help scientists distinguish between different types of cells) with hematopoietic stem cells (HSCs). The similarity in these surface markers between mast cells […]
A new model to expand blood stem cells
In a Molecular Systems Biology paper released this week, our team at the University of Toronto revealed a new mathematical model that links functional cellular assays to specific model outputs, defines cell-level kinetic parameters such as cell cycle rates and self-renewal probabilities as functions of culture variables, and simulates feedback regulation using cell–cell interaction networks. […]
Mending broken hearts
Cardiovascular disease accounts for the death of more Canadians than any other disease, more than 72,000 people each year. There is currently no cure for heart failure, and goals for treatment have always been to improve symptoms, stop the condition from getting worse, and prolong life span. But results from recent stem cell trials point […]
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