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The dermal cup, home to the elusive dermal stem cell

> The scientific community has long sought to uncover the identity of a true dermal stem cell. While many unique cell populations have been described in the literature, some of which are predictive of a dermal stem cell, the exact location and behavior of this cell...

Right Turn: Blockbuster toy or super (silly) biomaterial?

. Signals’ mandate is to bring you, dear reader, blogs about stem cells, commercialization and biomaterials, but lately there hasn’t been much of the latter; therefore, I’ve decided to try to fill that gap. But before you get too excited, I am in no way an expert on...

Bad luck, bad science, or bad reporting?

. If you’ve been on the Internet at all in 2015, you’ve probably stumbled across headlines like “Two-thirds of cancers are due to ‘back luck,’ study finds” (CBSNews), “Most cancers are caused by bad luck not genes or lifestyle say scientists” (The Telegraph), “Cause...

Update from the Clinic: December

. Welcome to your Update from the Clinic for the month of December. bluebird bio’s first four patients are transfusion-free after treatment with its gene therapy Lentiglobin. Fate Therapeutics’ hematopoietic stem cell-modulating technology ProHema seems to be on track...

Right Turn: Bands and bandages

. If you’ve never heard of epidermolysis bullosa (EB), you’re not alone. This rare genetic disease, which occurs in one of 20,000 births, creates fragile skin that tears at the slightest touch and results in blisters, sores and scar tissue. There is no cure. EB...