.
In 2012, Deborah Lieu from the University of California, Davis was granted $1.3 million by the California Institute for Regenerative Medicine (CIRM) to develop pacemaking cells from human induced pluripotent stem cells (HiPSCs) to replace electronic pacemakers. I first wrote about this in Keeping pace with stem cell technology.
With Valentine’s Day just a week away and “hearts” on everyone’s minds, I was curious to know how her work is progressing. From what I can tell, the research is still ongoing but I can’t find a new study. Here is her Year 2 progress report from CIRM’s website:
We continued our work in improving the yield of pacemaking cells from human induced pluripotent stem cells (hiPSCs) that can be used to engineer biopacemakers. The ion channel isoform responsible for the induced membrane potential changes in hiPSCs and their differentiating cardiac progeny was determined. We focused on optimizing the duration and the timing of membrane potential manipulation in improving the efficiency of pro-pacemaking cardiac progenitor cells and pacemaking cells.
Unless Dr. Lieu has planned to announce a new study in time for February 14th, we may be waiting a while to learn more.
So now that I’ve piqued your curiosity and disappointed you, maybe some humour can compensate. Here is more cute and clever Valentine’s-appropriate marketing from Life Technologies. Vote for your favourite here. (I promise that Life Tech doesn’t pay me to write about them. Cross my heart.)
Our regular feature, Right Turn, appears every Friday and we invite you to submit your own blog to info(at)ccrm.ca. We encourage you to be creative and use the right (!) side of your brain. We dare you to make us laugh! Right Turn features cartoons, photos, videos and other content to amuse, educate and encourage discussion.
As always, we welcome your feedback in the comment section.
Stacey Johnson
Latest posts by Stacey Johnson (see all)
- Right Turn: Can Bryan Johnson live forever? Will regenerative medicine help him do so? - October 10, 2025
- Right Turn: #pinksocks, diabetes news and other ramblings - June 24, 2025
- Right Turn: Some takeaways from Advanced Therapies Week 2025 - January 31, 2025




Comments