Privacy Policy
Signals Blog

Contributors

Categories

Holly Wobma

Holly completed an MD-PhD at Columbia University in New York during which she conducted graduate training in the lab of Gordana Vunjak-Novakovic and helped co-found a cell therapy company called Immplacate. She will soon be starting (June 2019) as a pediatric resident at the Boston Combined Residency Program and is interested in developing and translating cell and gene therapies for pediatric disease.

Posts by: Holly


Calling attention to collagen, the lesser known “triple” helix

Author: Holly Wobma, 11/24/14

> For anyone who follows crime dramas, you’ve probably come across the token episode where the resident computer genius pulls up a double helix to unravel some genetic clue about an elusive villain. Of course, most people know that the information in DNA requires more than a few clicks of the “zoom” button. But my […]

Sugar rush: The development of glucose-sensitive beta cells from embryonic precursors

Author: Holly Wobma, 10/06/14

> “Wow, my mouth just got diabetes.” Such are my immediate thoughts after taking a bite out of a red velvet cupcake.  Though I must qualify: by cupcake, I mean a skyscraper of frosting carefully balanced on a minimal crumbly foundation. Making such a hyperbolic statement heightens our awareness that diabetes involves intolerably high blood […]

Gene editing technique makes disease study almost as easy as flipping a switch

Author: Holly Wobma, 08/05/14

> Imagine you are about to interview someone, and rather than receiving a full reference letter, your candidate is described with but a single word. Do you think you’d get the whole picture? Of course you wouldn’t, but depending on the word chosen, you could make a decision. For example, “disorganized” or “unreliable” seem like […]

Sociology and stem cells: a lesson in natural self-healing and why some of us may be better at it

Author: Holly Wobma, 05/13/14

> I think one of the most universally embraced ideas when people gather together and pontificate about how their relatives or colleagues turned out they way they did, is that ‘people are a product of their environment’. I’m not here to make a singular stand against this notion — in fact, it certainly can explain […]

Immunology and insider dealing: How macrophages trick your body into accepting biomaterials

Author: Holly Wobma, 03/18/14

> I’d like to make an unusual proposition. It’s occurred to me that our bodies are kind of snobs. Personality aside, our bodies are extremely particular. They reject tons of bacteria and viruses, while accepting others. They reject foreign tissues but can sometimes be coaxed into accepting them when bribed with medications. I suppose you […]