Sara M. Nolte
Sara Nolte holds a Bachelor of Health Sciences and Masters of Science in Biochemistry & Biomedical Sciences from McMaster University. Her MSc research focused on developing a cancer stem model to study brain metastases from the lung. She then spent a year working on developing cell-based cancer immunotherapies. Throughout a highly productive graduate career, Sara became interested in scientific communication and education, and later pursued a career as a Physician Assistant (PA) in order to build medical expertise. Working as a PA in Emergency Medicine helps her find ways to bridge the gaps between laboratory and clinical science, and to improve scientific and health-related communication with the public. Outside of science, Sara enjoys participating in a variety of sports, and is a competitive Olympic weightlifter hoping to compete at the National level soon!
Posts by: Sara M.
Just a “nibble”: New research on the cancer and natural killer cell relationship
Almost two years ago, I wrote a post about how scientists were looking for new immunotherapies to improve immunologically “cold” tumours’ responses to existing therapies. And while the findings of that article were very promising, tumour evasion of the immune system continues to vex cancer researchers. A recent study, led by Dr. Michele Ardolino from […]
Genetically engineering cures for sickle cell disease
If I were to ask you to think of a genetic disease that should be a priority for gene therapy research, you might say breast cancer, Huntington’s, or cystic fibrosis. And these are all great candidates. But I’d say you’re missing a big one. Sickle cell disease (SCD) is often overlooked, much like the population […]
Diabetes research in Canada: 100 years later
2021 marked the 100th anniversary of the discovery of insulin – a Canadian breakthrough that has saved the lives of countless people with diabetes. It seems only fitting that 100 years later, we take a moment to reflect on how far Canadian diabetes research has come, with a focus on stem cells and regenerative […]
Using immunotherapy to make cold tumours immunological hotbeds
Cancer immunotherapy is so hot right now. Signals bloggers have covered CAR T cells (here and here), but haven’t given some other exciting immunotherapies their time to shine. I aim to correct that. A normal part of the immune system, checkpoints are a mechanism to prevent the immune response from running rampant and destroying host […]
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