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Adult stem cells keep you roadworthy

How do adult stem cells work? In healthy tissue the adult stem cell population lies dormant. Dormant stem cells are activated by external trauma signals, which trigger patterns of gene expression and protein biosynthesis, thus activating the stem cells to multiply and...

A revised map for blood development

Simple diagram that shows the development of different blood cells from  hematopoietic stem cell to mature cells. From Wikipedia. All blood cells arise from the common hematopoietic stem cell and are classified into two lineages: lymphoid cells (B-, T- and Natural...

Regenerative therapies using scaffolds

When using stem cells for regenerative therapies, there are a few approaches that can be taken. Donor cells have issues with matching and immune rejection. Autologous stem cells transplants skirt rejection issues, but both strategies still face challenges associated...

A closer look at stem cell tourism

  For centuries, “snake oil salesmen” have used cleverly crafted acts to peddle fake medicines. The modern-day version of the medical conman has zeroed on stem cells, selling treatments with unproven effects and unknown risks. Using online marketing campaigns, stem...

Modeling ALS using patient-derived iPS cells

The UK-based Motor Neurone Disease Association has recently funded a £800,000 ($1.2 million) program to study motor neurons derived from the skin cells of amyotrophic lateral sclerosis (ALS) patients with rare, disease-causing mutations in the gene TARBP. Although the...

In the blood – part one

Part one in a series looking at the processes involved in the most clinically applied form of stem cell therapy: hematopoietic stem cell transplantation Leukocytes, or white blood cells (WBCs), are an essential part of the immune system. Produced in the bone marrow,...

Scaling up stem cells for clinical use

The potential gains from stem cell research are unlimited; stem cells could be used to replace degenerated cells and tissue in the human body. However, the large scale implementation of stem cell therapy to a clinical setting will require the establishment of a...

New summary on stem cell research for ALS

Amyotrophic lateral sclerosis (ALS), known as Lou Gehrig’s Disease and motor neuron disease (MND), is a progressive neuromuscular disease that attacks nerve cells in the brain and spinal cord. As these neurons slowly waste away, they become unable to transmit signals...

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