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A revised map for blood development

Simple diagram that shows the development of different blood cells from  hematopoietic stem cell to mature cells. From Wikipedia. All blood cells arise from the common hematopoietic stem cell and are classified into two lineages: lymphoid cells (B-, T- and Natural...

Regenerative therapies using scaffolds

When using stem cells for regenerative therapies, there are a few approaches that can be taken. Donor cells have issues with matching and immune rejection. Autologous stem cells transplants skirt rejection issues, but both strategies still face challenges associated...

Modeling ALS using patient-derived iPS cells

The UK-based Motor Neurone Disease Association has recently funded a £800,000 ($1.2 million) program to study motor neurons derived from the skin cells of amyotrophic lateral sclerosis (ALS) patients with rare, disease-causing mutations in the gene TARBP. Although the...

Scaling up stem cells for clinical use

The potential gains from stem cell research are unlimited; stem cells could be used to replace degenerated cells and tissue in the human body. However, the large scale implementation of stem cell therapy to a clinical setting will require the establishment of a...

iPS cells can help speed traditional drug development

Imagine that you’ve just discovered a novel drug that potentially solves a medical problem, one that accelerates wound healing in skin or can reduce the size of cancerous tumors. You can show the effects beautifully in your model tissue culture system and mice...