by Paul Krzyzanowski | Nov 17, 2010
In a previous post, Chris Kamel recently reviewed the Nature article about direct creation of blood progenitors from skin fibroblasts as discovered by Mick Bhatia’s research group. The fascinating thing about this article is the potential for enabling autologous...
by David Kent | Nov 10, 2010
One of the most memorable moments of my PhD training was at a 2006 Keystone conference where Shinya Yamanaka presented a little something called Pluripotency and Nuclear Reprogramming. He carefully presented the transcription factor screen that would culminate in the...
by Chris Kamel | Nov 7, 2010
Though methods to convert adult cells into induced pluripotent stem (iPS) cells continue to improve, transition from the lab bench to the clinic can be a trickier proposition. Due to imperfect efficiency, each manipulation — conversion of adult cell to iPS cell...
by Katie Moisse | Nov 5, 2010
In 2009, surgeons transplanted 2,155 organs — nearly a quarter of which were livers – from live or deceased donors into grateful recipients. Sadly, another 3,796 Canadians remained on the transplant wait list, and 249 died while waiting, according to the...
by Chris Kamel | Oct 19, 2010
As mentioned in a previous post, in order to fully understand what’s happening when stem cells are used for in clinical or in vivo research, we need some way to track them, preferably in a non-invasive manner. This can be done with either reporter genes or some...
by Chris Kamel | Oct 14, 2010
The reprogramming of differentiated adult cells into induced pluripotent stem (iPS) cells is accomplished by the expression of a small number of key genes. This is typically done by introducing DNA either by transfection or with viral vectors. Current methods,...
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