by David Kent | Nov 10, 2010
One of the most memorable moments of my PhD training was at a 2006 Keystone conference where Shinya Yamanaka presented a little something called Pluripotency and Nuclear Reprogramming. He carefully presented the transcription factor screen that would culminate in the...
by Chris Kamel | Nov 7, 2010
Though methods to convert adult cells into induced pluripotent stem (iPS) cells continue to improve, transition from the lab bench to the clinic can be a trickier proposition. Due to imperfect efficiency, each manipulation — conversion of adult cell to iPS cell...
by Katie Moisse | Nov 5, 2010
In 2009, surgeons transplanted 2,155 organs — nearly a quarter of which were livers – from live or deceased donors into grateful recipients. Sadly, another 3,796 Canadians remained on the transplant wait list, and 249 died while waiting, according to the...
by Chris Kamel | Oct 19, 2010
As mentioned in a previous post, in order to fully understand what’s happening when stem cells are used for in clinical or in vivo research, we need some way to track them, preferably in a non-invasive manner. This can be done with either reporter genes or some...
by Chris Kamel | Oct 14, 2010
The reprogramming of differentiated adult cells into induced pluripotent stem (iPS) cells is accomplished by the expression of a small number of key genes. This is typically done by introducing DNA either by transfection or with viral vectors. Current methods,...
by Allison Van Winkle | Oct 8, 2010
High-throughput screening, in which many cell culture conditions can be tested using a combination of robotics, control software, and/or highly sensitive detection, allows researchers to explore new ideas quickly; thousands of combinations can be efficiently tested...
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