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Right Turn: Animals, ethics and Orwell

Much has been said on the topic of using animals for medical/scientific research. There are excellent and compelling arguments for and against the issue and my plan is to avoid taking a stand here. (You may be tempted to call me chicken, but that would be a really bad...

Right Turn: Making a fashion statement with stem cells

Straight from the laboratory to the runway, it looks like stem cells have gone haute couture. Fashion designer Dominic Pangborn has teamed up with a group of researchers from the Heinz C. Prechter Bipolar Research Fund at the University of Michigan to create a...

Update from the Clinic: May

Welcome to your update from the clinic for the month of May. Long-standing industry pioneer StemCells, Inc. decided to wind down its operations after a failed Phase 2 study in spinal cord injury. Aduro Biotech also saw a failure with its GVAX product in pancreatic...

Extracellular vesicles, the next Minions?

This post was authored by Kelvin Ng and James Smith. Completing his PhD this year in the Karp lab at MIT/Harvard, Kelvin focuses on strategies and technologies that guide or accelerate the translation of therapeutic extracellular vesicles. His multidisciplinary...

ISSCR Day 1: Escaping the ground state of pluripotency

The 2016 Annual Meeting of the International Society for Stem Cell Research got off to a fantastic start Wednesday night in San Francisco. Two excellent sessions were delivered to a packed house with talks ranging from the importance of circular RNAs (Pier Paolo...

Cell Therapy Deal Review: May

Welcome to your deal review for the month of May. Intellia Therapeutics went public this past month giving investors a second shot on net if they want to gain exposure to gene editing technologies. Caladrius Biosciences spun-out its cell-based immunotherapy to AiVita...

Right Turn: Could this rhino-sized rescue plan really work?

Peanut butter and jelly. Macaroni and cheese. Fish and chips. Some things are just better paired together. But there’s one combination you’d never expect to see: surrogate rhinos and stem cells.    With just three northern white rhinos left on earth, it looks like...

Ugly duckling spreads its wings

  When Dr. Andras Nagy, a Senior Scientist at Sinai Health System’s Lunenfeld-Tanenbaum Research Institute in Toronto, set out to catalogue molecular events behind reprogramming — a process of making stem cells in a dish ­— he did not expect to uncover a new kind...

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